Ketamine AnswersKetamine & SPRAVATO® · Review
The Best Ketamine Clinics in Denver: 2026 Review
By the Ketamine Answers team · Reviewed against our methodology · Updated October 2026
"Ketamine clinic" in Denver can mean a certified SPRAVATO® program, a supervised ketamine therapy practice, an infusion center, or a psychiatry group that offers one of these inside broader care — and the differences decide cost, coverage, and safety. We reviewed Denver-metro providers on the criteria in our methodology, weighting supervision model, whether both pathways are available in one practice, what the practice offers if ketamine-based treatment is not the fit, insurance access for the covered pathway, and honesty about what is FDA-approved and what is off-label. Every provider listed is legitimate; the ranking reflects comparison on those criteria. Where a listed clinic shares ownership with this site, that relationship is disclosed at the listing itself and on our disclosure page.
1. TMS Therapy Centers Colorado · Aurora
TMS Therapy Centers Colorado shares ownership with this publication. See our full disclosure.
The metro's reference point for both ketamine-based pathways under one psychiatrist: certified SPRAVATO® (esketamine) treatment and physician-supervised ketamine therapy, alongside FDA-cleared TMS and medication management, founded by board-certified psychiatrist Dr. William Kromka, MD. Most major insurance including Medicare and TRICARE; 720-500-7873; 2821 S Parker Rd, Suite 877, Aurora.
Visit website ↗2. Denver TMS Therapy · Denver, LoHi
Denver TMS Therapy shares ownership with this publication. See our full disclosure.
Central Denver's physician-led clinic with SPRAVATO® in a certified, monitored setting and off-label ketamine therapy under psychiatric supervision, plus TMS if neither is the fit. Insurance accepted for SPRAVATO® and TMS; TRICARE-authorized; (720) 214-2770.
Visit website ↗3. Denver Ketamine Clinic · Denver, Washington Park West
Denver Ketamine Clinic shares ownership with this publication. See our full disclosure.
Built specifically around ketamine-based treatment: FDA-approved SPRAVATO® and physician-supervised ketamine therapy, with the distinction between them — approval, coverage, cost — explained before any decision, and TMS available in the same clinic. Founded by Dr. Kromka; 66 S Logan St; (720) 221-8560.
Visit website ↗4. Bluebird TMS · Greenwood Village, DTC
Bluebird TMS shares ownership with this publication. See our full disclosure.
The south-metro option for SPRAVATO® and ketamine therapy at a Denver Tech Center clinic built around a workday, with TMS and medication management under the same roof. TRICARE-authorized; 7447 E Berry Ave, Suite 150; (720) 716-8469.
Visit website ↗5. Klarisana · Denver
A dedicated ketamine-treatment organization with institutional experience in ketamine-based care, including SPRAVATO® — the metro's most established name for a ketamine specialist.
Visit website ↗6. Axis Integrated Mental Health · Aurora, Westminster, DTC, Louisville
SPRAVATO® within a psychiatry and therapy practice with four metro clinics, plus deep TMS — a multi-path option for patients who want therapy coordinated with treatment.
Visit website ↗7. Denver Wellness Associates · Denver metro
An established psychiatry group offering SPRAVATO® and TMS within full psychiatric services across multiple locations.
Visit website ↗8. Balanced Mental Wellness · Denver metro
A Denver-metro mental-health practice offering ketamine-based treatment within psychiatric care.
Visit website ↗9. Rocky Mountain Mind & Body · Denver metro
A Denver-metro provider offering ketamine treatment for mood conditions.
Visit website ↗
How to choose among them
First, which pathway: if you meet treatment-resistant depression criteria and have insurance, certified SPRAVATO® is usually the affordable route; ketamine therapy is off-label and self-pay. Second, supervision — every clinic above is in-clinic and monitored; understand that before comparing with at-home options. Third, what happens if this is not the answer — a practice with TMS or psychiatry in-house turns non-response into a next step. Fourth, the ride home: you cannot drive after a session.